Author: Avi Sheshachalam
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Fashionable AI and the Future of Work
There was a time when clothes were made slowly. They were hand-stitched, hand-dyed, and deeply personal. In India, crafts like Kalamkari used hand-drawn patterns and natural dyes to create fabrics that weren’t just beautiful — they told stories. Across the world, in small workshops and home studios, garments came to life with a sense of… Read more
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Moving Fast and Moving Right – Process Mapping
Calm Growth by Avi Need help process mapping complex manufacturing? Read more
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America’s Loss Could Be Canada’s Gain: An Open Invitation to Innovators and Regulators
In recent weeks, thousands of scientists, regulators, policy experts, and statisticians have lost their jobs as part of sweeping government efficiency moves in the United States. These aren’t just numbers on a spreadsheet—these are individuals who have spent their careers ensuring that innovation is safe, effective, and accessible. The people behind FDA approvals, NIH funding,… Read more
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What to Build: Startups for the Future of Work
The future of work is a mashup of big shifts—automation, green transitions, and the digital revolution—all happening at once. As the World Economic Forum’s Future of Jobs Report 2025 points out, certain industries are booming while others are phasing out faster than your Wi-Fi during a Zoom call. If you’re an entrepreneur, this isn’t just… Read more
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San Francisco or the Shadows: Where Should Startups Build?
A Look at Why San Francisco is Winning the VC Game (Again) and How Canada Can Still Play a Smart Hand Show Me the Money (Stats, Stats, Stats!) 2024 was a blockbuster year for Silicon Valley. The region gobbled up over half of all global VC dollars, according to TechCrunch. That’s not just dominance –… Read more
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AI: Everything, Everywhere, All at Once; FDA: now, wait a second!
Artificial Intelligence is no longer just a fancy tool for predicting protein structures with AlphaFold. The FDA’s new draft guidelines outline a vision where AI permeates every stage of drug and biologics development. Whether it’s identifying drug targets, optimizing manufacturing, or—yes—even drafting Standard Operating Procedures (SOPs), AI is now under the regulatory spotlight. And here’s… Read more
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Longevity in the Age of Depopulation
If there’s one thing the biotech world loves, it’s a good hype cycle. We’ve seen it with CRISPR, stem cells, mRNA vaccines, and synthetic biology. But what if I told you that the next big biotech wave isn’t about curing cancer or building lab-grown burgers? No, the next frontier is far grander: solving aging itself.… Read more
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Catching Big Pharma’s attention
Catching Big Pharma attention by Avi We focus on every detail so you can relax. Let us help you tell your story Calmly. Persuasively. Memorably 🎉 We take celebrating to the next level Read more
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Biotech dreams & Startup nightmares
Let me take you back to a time when Avatar was breaking box office records, everyone was pretending to love quinoa, and I was an eager Master’s student interning at a small biotech startup. Let’s call it…BioHopeful Inc. (to spare feelings). The Product That Could Have Been a StarAt the core of BioHopeful’s ambitions was… Read more
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Three Big Questions for Canada’s Innovation Ecosystem
A Reality Check on Our Productivity Crisis Canada’s innovation ecosystem feels like a group project where everyone’s working hard, but nobody’s quite sure who’s in charge. We’ve got the brains, the ambition, and a few gold stars on the global stage, but productivity numbers tell a different story. According to Stats Canada, labour productivity in… Read more